The game was cancelled after 18 Leyton players tested positive for COVID-19.
Information gathered revealed that Spurs maybe handed a pass into the next round according to EFL rules, where they will face Chelsea.
Premier League champions, Liverpool will welcome Arsenal, while Manchester City travel to Burnley next week.
Aston Villa host Stoke City in the next round and Manchester United are away at Brighton.
The fourth round draw in full:
Liverpool vs Arsenal
Burnley vs Manchester City
Brentford vs Fulham
Everton vs West Ham
Aston Villa vs Stoke City
Leyton Orient/Tottenham Hotspur vs Chelsea
Newport County vs Newcastle United
Brighton & Hove Albion vs Manchester United